Article produced in collaboration with Erbavita
Biologically, aging is the progressive accumulation of molecular damage and the loss of cellular homeostasis. Gerontological research consolidates this decline into the Hallmarks of Aging, identifying its key drivers:
- Mitochondrial dysfunction: the decline in NAD+ undermines the respiratory chain and ATP production.
- Loss of autophagy: deficits in endogenous recycling systems lead to the buildup of proteotoxic waste.
- Cellular senescence: senescent (non-dividing) cells secrete pro-inflammatory cytokines that fuel inflammaging.
- DNA damage and oxidative stress: impaired genomic stability damages the vascular endothelium.
- Neuro-cognitive decline: reduced synaptic plasticity and microcirculatory distress alter neural signaling.
Mapping these processes is the only way to intervene effectively. It is precisely on this biological map that Erba Vita designed the Longevity Platinum line: a targeted, selective, and sequential nutraceutical response crafted to act on the individual drivers of aging.
CELLULAR RESTART | Metabolic Reset and Autophagy (20-day Protocol)
A two-phase, sequential intervention applying the Pulse Treatment logic: rather than a continuous stimulus, it delivers a brief, concentrated impulse to guide renewal without interfering with physiological repair processes:
Phase 1 (days 1-15) – Systemic Optimization:
Nicotinamide Riboside Chloride (300 mg): a highly stable, bioavailable precursor that directly penetrates the cell via a specific transporter, restoring NAD+ levels and mitochondrial function.
Spermidine Semprevital® (2.5 mg) + Betaine (200 mg): spermidine initiates autophagic mechanisms to clear cellular waste, while Betaine supports the methylation cycle.
Phase 2 (days 16-20) – Senolytic Reset:
Fisetin (200 mg) + Quercetin (50 mg) + Piperine (4.75 mg): a combination of senolytic flavonoids aimed at promoting the clearance of senescent cells and turning off inflammaging. Piperine inhibits glucuronidation, allowing the active ingredients to reach systemic circulation.
BRAIN DEFENCE | Neuroprotection and Cerebral Bioenergetics
Directed at maintaining neuronal plasticity, memory, and cortical blood flow in contexts of cognitive fatigue or prevention of neuro-sensory decline:
Citicoline Cognizin® (500 mg): a fermentation-derived citicoline of exceptionally high purity that supports brain energy metabolism, preserves neuronal membrane integrity and neurotransmitter synthesis, promoting mental clarity, focus, and memory. Cognizin® has more than 6 published clinical studies.
Ginkgo biloba (150 mg, 36 mg ginkgoflavones): supports cerebral microcirculation and tissue oxygenation.
Vitamin B12 in dual form (500 µg): combines Methylcobalamin (active form) and Cyanocobalamin (highly stable form) for homocysteine control and myelin sheath protection.
RESVERATROL SimbiΩ®| Sirtuin Activator and Endothelial Shield
Developed to activate the sirtuin deacetylase (SIRT1), promote DNA stability, and protect cardiovascular and neurological systems:
Resveratrol SimbiΩ® patent (150 mg Trans-Resveratrol): a plant-based lipid carrier that overcomes rapid first-pass hepatic/intestinal metabolism, increasing systemic absorption by up to +50% within the first five minutes compared with standard trans-resveratrol.
Pterostilbene (10 mg from Indian kino): a lipophilic analog of resveratrol with a longer half-life and sustained tissue presence.
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